Simultaneous Spectrophotometric Determination of Valsartan and Ezetimibe in Pharmaceuticals
نویسندگان
چکیده
منابع مشابه
Simultaneous Spectrophotometric Determination of Ezetimibe and Simvastatin in Pharmaceutical Preparations Using Chemometric Techniques
Two spectrophotometric methods are described for the simultaneous determination of ezetimibe (EZE) and simvastatin (SIM) in pharmaceutical preparations. The obtained data was evaluated by using two different chemometric techniques, Principal Component Regression (PCR) and Partial Least-Squares (PLS-1). In these techniques, the concentration data matrix was prepared by using the mixtures contain...
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Three sensitive methods were developed for simultaneous determination of Ezetimibe (EZB) and Atorvastatin calcium (ATVC) in binary mixtures. First derivative (D(1)) spectrophotometry was employed for simultaneous determination of EZB (223.8 nm) and ATVC (233.0 nm) with a mean percentage recovery of 100.23 ± 1.62 and 99.58 ± 0.84, respectively. Linearity ranges were 10.00-30.00 μg mL(-1) and 10....
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A spectrophotometric method was developed for simultaneous determination of amlodipine (Aml) and valsartan (Val) without previous separation. In this method amlodipine in methanolic solution was determined using zero order UV spectrophotometry by measuring its absorbency at 360.5 nm without any interference from valsartan.Valsartan spectrum in zero order is totally overlapped with that of amlod...
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BACKGROUND AND THE PURPOSE OF THE STUDY The linear multivariate calibration models such as principal components regression (PCR) and partial least squares regressions (PLS1 and PLS2) due to the mathematical simplicity and physical or chemical interpretability are sufficient and generally preferred method for analysis of multicomponent drugs. In this study, simultaneous determination of paraceta...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2011
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v10i6.15